01:03:03 Europe / Stockholm

Bifogade filer

Kurs & Likviditet

Kursutveckling och likviditet under dagen för detta pressmeddelande


2023-11-08 Kvartalsrapport 2023-Q3
2023-08-16 Kvartalsrapport 2023-Q2
2023-05-10 Kvartalsrapport 2023-Q1
2023-03-22 Ordinarie utdelning HLUN A 0.58 DKK
2023-03-22 Ordinarie utdelning HLUN B 0.58 DKK
2023-03-21 Årsstämma 2023
2023-02-08 Bokslutskommuniké 2022
2022-11-09 Kvartalsrapport 2022-Q3
2022-08-17 Kvartalsrapport 2022-Q2
2022-06-10 Split HLUN B 1:5
2022-06-08 Extra Bolagsstämma 2022
2022-05-11 Kvartalsrapport 2022-Q1
2022-03-24 Ordinarie utdelning HLUN B 2.00 DKK
2022-03-23 Årsstämma 2022
2022-02-09 Bokslutskommuniké 2021
2021-11-10 Kvartalsrapport 2021-Q3
2021-08-18 Kvartalsrapport 2021-Q2
2021-05-11 Kvartalsrapport 2021-Q1
2021-03-24 Ordinarie utdelning HLUN B 2.50 DKK
2021-03-23 Årsstämma 2021
2021-02-04 Bokslutskommuniké 2020
2020-11-03 Kvartalsrapport 2020-Q3
2020-08-13 Kvartalsrapport 2020-Q2
2020-05-12 Kvartalsrapport 2020-Q1
2020-03-25 Ordinarie utdelning HLUN B 4.10 DKK
2020-03-24 Årsstämma 2020
2020-02-06 Bokslutskommuniké 2019
2019-11-05 Kvartalsrapport 2019-Q3
2019-08-14 Kvartalsrapport 2019-Q2
2019-05-08 Kvartalsrapport 2019-Q1
2019-03-27 Ordinarie utdelning HLUN B 12.00 DKK
2019-03-26 Årsstämma 2019
2019-02-05 Bokslutskommuniké 2018
2018-11-07 Kvartalsrapport 2018-Q3
2018-08-08 Kvartalsrapport 2018-Q2
2018-05-08 Kvartalsrapport 2018-Q1
2018-03-21 Ordinarie utdelning HLUN B 8.00 DKK
2018-03-20 Årsstämma 2018
2018-02-07 Bokslutskommuniké 2017
2017-11-08 Kvartalsrapport 2017-Q3
2017-08-09 Kvartalsrapport 2017-Q2
2017-05-10 Kvartalsrapport 2017-Q1
2017-03-31 Ordinarie utdelning HLUN B 2.45 DKK
2017-03-30 Årsstämma 2017
2017-02-08 Bokslutskommuniké 2016
2016-11-02 Kvartalsrapport 2016-Q3
2016-08-24 Kvartalsrapport 2016-Q2
2016-05-11 Kvartalsrapport 2016-Q1
2016-04-01 Ordinarie utdelning HLUN B 0.00 DKK
2016-03-31 Årsstämma 2016
2016-02-10 Bokslutskommuniké 2015
2015-11-04 Kvartalsrapport 2015-Q3
2015-08-19 Kvartalsrapport 2015-Q2
2015-05-06 Kvartalsrapport 2015-Q1
2015-03-26 Ordinarie utdelning HLUN B 0.00 DKK
2015-03-25 Årsstämma 2015
2015-02-05 Bokslutskommuniké 2014
2014-11-05 Kvartalsrapport 2014-Q3
2014-08-07 Kvartalsrapport 2014-Q2
2014-05-07 Kvartalsrapport 2014-Q1
2014-03-27 Ordinarie utdelning
2014-03-26 Årsstämma 2014
2014-02-06 Bokslutskommuniké 2013
2013-11-06 Kvartalsrapport 2013-Q3
2013-08-07 Kvartalsrapport 2013-Q2
2013-05-01 Kvartalsrapport 2013-Q1
2013-03-22 Ordinarie utdelning
2013-03-21 Årsstämma 2013
2013-02-06 Bokslutskommuniké 2012
2012-03-30 Ordinarie utdelning
2011-03-31 Ordinarie utdelning
2010-04-21 Ordinarie utdelning
2009-04-22 Ordinarie utdelning


ListaLarge Cap Copenhagen
IndustriLäkemedel & Handel
Lundbeck är ett läkemedelsbolag. Störst fokus återfinns inom forskning om psykiatriska och neurotiska störningar, vilket innefattar behandling av depression, schizofreni, Alzheimers och Parkinsons syndrom. Bolaget bedriver forskning, utveckling och vidare distribution av läkemedel där kunderna återfinns på global nivå. Bolaget grundades 1915 och har sitt huvudkontor i Valby.
2020-09-17 08:01:42

The study, which assessed treatment with vortioxetine for emotional blunting in Major Depressive Disorder (MDD), was presented for the first time at the European College of Neuropsychopharmacology 2020 congress.

H. Lundbeck A/S (Lundbeck) announces a new study that finds reduction in emotional blunting for people living with Major Depressive Disorder when treated with vortioxetine. In total, 150 patients were enrolled in the study called COMPLETE. A significant improvement in symptoms of emotional blunting as measured by Oxford Depression Questionnaire (ODQ) was observed after only one week of treatment; a benefit that continued to increase up until the end of study.

Emotional blunting is a common symptom of MDD and is clinically important as it prevents full recovery. It is experienced by half of all patients treated with SSRIs (Selective Serotonin Reuptake Inhibitors) or SNRIs (Serotonin-Norepinephrine Reuptake Inhibitor).

"Blunted emotions are well-recognized to have functional consequences on patients' social, family and work life. It is a severe symptom to people who are seeking full recovery from Major Depressive Disorder. We are pleased to be able to share such positive data with the wider neuroscience community," says Johan Luthman, EVP Research and Development

Patients in the study had been treated at adequate dose for at least six weeks with either an SSRI or SNRI and suffered from emotional blunting prior to entering this 8-week open-label study. After eight weeks of treatment with vortioxetine, 50% of the patients reported they did not experience this symptom anymore. A significant improvement in patients psychosocial functioning as measured by the Sheehan Disability Scale (work, family and social life) was also observed.

Based on the mechanism of actions, in particular modulation of 5-HT3 and the downstream positive effect on dopamine, the results of this study appear to support that vortioxetine may have a positive effect on emotional blunting.The results are encouraging as they show that emotional blunting potentially can be addressed by switching medication and lead to a significant improvement in their overall functioning in daily life.   

The key data from the study was presented on the occasion of the 33rd ECNP Congress Virtual with educational financial support provided by Lundbeck.

About emotional blunting
About 50% of all patients treated with SSRIs or SNRIs suffer from emotional blunting[i] (http://#_edn1). This symptom is a clinical state where both positive and negative emotions are toned down or flattened. It leaves patients feeling indifferent to many aspects of their life that should matter to them such as their family, friends, and their job. The symptoms are particularly prominent when patients reach remission from their core symptoms of depression and re-engage in activities of their normal life that have been reduced or put on hold during the acute phase of their illness. Living with emotional blunting is unacceptable for many patients with MDD and it is a very common reason for stopping medication.

About vortioxetine
The mechanism of the antidepressant effect of vortioxetine is not fully understood. It is an inhibitor of serotonin (5-HT) reuptake and that is thought to be a mechanism of its action. It is also an agonist at 5-HT\1A\ receptors, a partial agonist at 5-HT\1B\ receptors and an antagonist at 5-HT\3\, 5-HT\1D\ and 5-HT\7\ receptors. The contribution of each of these activities to vortioxetine's antidepressant effect has not been established. It is considered to be the first and only compound with this combination of pharmacodynamic activity. The clinical relevance of this is unknown. Vortioxetine was discovered by Lundbeck researchers in Copenhagen, Denmark. Depending on the market, vortioxetine is known as Trintellix[®] or Brintellix[®].


Mikkel Ballegaard Pedersen
Communication Consultant, Corp. Communication
+45 30 83 20 44

About Lundbeck
H. Lundbeck A/S (LUN.CO, LUN DC, HLUYY) is a global pharmaceutical company specialized in brain diseases. For more than 70 years, we have been at the forefront of neuroscience research. We are tirelessly dedicated to restoring brain health, so every person can be their best.

Millions of people worldwide live with brain diseases and far too many suffer due to inadequate treatment, discrimination, a reduced number of working days, early retirement and other unnecessary consequences. Every day, we strive for improved treatment and a better life for people living with brain diseases - we call this Progress in Mind.

Our approximately 5,800 employees in more than 50 countries are engaged in the entire value chain throughout research, development, production, marketing and sales. Our pipeline consists of several R&D programs and our products are available in more than 100 countries. We have research centers in Denmark and the US and our production facilities are located in Denmark, France and Italy. Lundbeck generated revenue of DKK 17.0 billion in 2019 (EUR 2.3 billion; USD 2.6 billion).

For additional information, we encourage you to visit our corporate site www.lundbeck.com and connect with us on Twitter at @Lundbeck (https://twitter.com/lundbeck) andvia LinkedIn (https://www.linkedin.com/company/lundbeck/).


[i] (http://#_ednref1) G M Goodwin et al. J Affect Disord. 2017