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2024-02-08 Bokslutskommuniké 2023
2023-11-09 Kvartalsrapport 2023-Q3
2023-08-10 X-dag halvårsutdelning AZN 9.64
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2023-04-27 Årsstämma 2023
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2023-02-09 Bokslutskommuniké 2022
2022-11-10 Kvartalsrapport 2022-Q3
2022-08-11 X-dag halvårsutdelning AZN 9.49
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2022-04-29 Kvartalsrapport 2022-Q1
2022-04-29 Årsstämma 2022
2022-02-24 X-dag halvårsutdelning AZN 18
2022-02-10 Bokslutskommuniké 2021
2021-11-12 Kvartalsrapport 2021-Q3
2021-08-12 X-dag halvårsutdelning AZN 7.72
2021-07-29 Kvartalsrapport 2021-Q2
2021-05-11 Årsstämma 2021
2021-04-30 Kvartalsrapport 2021-Q1
2021-02-25 X-dag halvårsutdelning AZN 15.76
2021-02-11 Bokslutskommuniké 2020
2020-11-05 Kvartalsrapport 2020-Q3
2020-08-13 X-dag halvårsutdelning AZN 7.87
2020-07-30 Kvartalsrapport 2020-Q2
2020-04-29 Årsstämma 2020
2020-04-29 Kvartalsrapport 2020-Q1
2020-02-27 X-dag halvårsutdelning AZN 18.32
2020-02-14 Bokslutskommuniké 2019
2019-10-24 Kvartalsrapport 2019-Q3
2019-08-08 X-dag halvårsutdelning AZN 8.49
2019-07-25 Kvartalsrapport 2019-Q2
2019-04-26 Kvartalsrapport 2019-Q1
2019-04-26 Årsstämma 2019
2019-02-28 X-dag halvårsutdelning AZN 17.46
2019-02-14 Bokslutskommuniké 2018
2018-11-08 Kvartalsrapport 2018-Q3
2018-08-09 X-dag halvårsutdelning AZN 7.92
2018-07-26 Kvartalsrapport 2018-Q2
2018-05-18 Kvartalsrapport 2018-Q1
2018-05-18 Årsstämma 2018
2018-02-15 X-dag halvårsutdelning AZN 14.97
2018-02-02 Bokslutskommuniké 2017
2017-11-09 Kvartalsrapport 2017-Q3
2017-08-10 X-dag halvårsutdelning AZN 7.4
2017-07-27 Kvartalsrapport 2017-Q2
2017-04-27 Årsstämma 2017
2017-04-27 Kvartalsrapport 2017-Q1
2017-02-16 X-dag halvårsutdelning AZN 16.57
2017-02-02 Bokslutskommuniké 2016
2016-11-10 Kvartalsrapport 2016-Q3
2016-08-11 X-dag halvårsutdelning AZN 7.81
2016-07-28 Kvartalsrapport 2016-Q2
2016-04-29 Kvartalsrapport 2016-Q1
2016-04-29 Årsstämma 2016
2016-02-18 X-dag halvårsutdelning AZN 16.26
2016-02-04 Bokslutskommuniké 2015
2015-11-05 Kvartalsrapport 2015-Q3
2015-08-13 X-dag halvårsutdelning AZN 7.71
2015-07-30 Kvartalsrapport 2015-Q2
2015-04-24 Kvartalsrapport 2015-Q1
2015-04-24 Årsstämma 2015
2015-02-19 X-dag halvårsutdelning AZN 15.62
2015-02-05 Bokslutskommuniké 2014
2014-11-06 Kvartalsrapport 2014-Q3
2014-08-13 X-dag halvårsutdelning AZN 6.2
2014-07-31 Kvartalsrapport 2014-Q2
2014-04-24 Kvartalsrapport 2014-Q1
2014-04-24 Årsstämma 2014
2014-02-19 X-dag halvårsutdelning AZN 12.41
2014-02-06 Bokslutskommuniké 2013
2013-10-31 Kvartalsrapport 2013-Q3
2013-08-14 X-dag halvårsutdelning AZN 5.92
2013-08-01 Kvartalsrapport 2013-Q2
2013-08-01 Analytiker möte 2013
2013-04-25 Kvartalsrapport 2013-Q1
2013-04-25 Årsstämma 2013
2013-02-13 X-dag halvårsutdelning AZN 12.08
2013-01-31 Bokslutskommuniké 2012
2012-10-25 Kvartalsrapport 2012-Q3
2012-10-25 Analytiker möte 2012
2012-08-08 X-dag halvårsutdelning AZN 6.26
2012-07-26 Kvartalsrapport 2012-Q2
2012-04-26 Kvartalsrapport 2012-Q1
2012-04-26 Årsstämma 2012
2012-02-15 X-dag halvårsutdelning AZN 13.21
2012-02-02 Bokslutskommuniké 2011
2011-10-27 Kvartalsrapport 2011-Q3
2011-08-03 X-dag halvårsutdelning AZN 5.33
2011-07-28 Kvartalsrapport 2011-Q2
2011-04-28 Årsstämma 2011
2011-04-28 Kvartalsrapport 2011-Q1
2011-02-02 X-dag halvårsutdelning AZN 11.99
2011-01-27 Bokslutskommuniké 2010
2010-10-28 Kvartalsrapport 2010-Q3
2010-08-04 X-dag halvårsutdelning AZN 5.12
2010-07-29 Kvartalsrapport 2010-Q2
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2010-02-03 X-dag halvårsutdelning AZN 12.43
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2009-10-29 Kvartalsrapport 2009-Q3
2009-08-05 X-dag halvårsutdelning AZN 4.41
2009-07-30 Kvartalsrapport 2009-Q2
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2009-04-30 Årsstämma 1
2009-02-04 X-dag halvårsutdelning AZN 12.02
2008-08-06 X-dag halvårsutdelning AZN 3.34
2008-02-06 X-dag halvårsutdelning AZN 8.61
2007-08-08 X-dag halvårsutdelning AZN 3.49
2007-02-07 X-dag halvårsutdelning AZN 8.6
2006-08-09 X-dag halvårsutdelning AZN 3.6
2006-02-08 X-dag halvårsutdelning AZN 7.02
2005-08-10 X-dag halvårsutdelning AZN 2.99
2005-02-09 X-dag halvårsutdelning AZN 4.497
2004-08-11 X-dag halvårsutdelning AZN 2.2
2004-02-18 X-dag halvårsutdelning AZN 3.91
2003-08-20 X-dag halvårsutdelning AZN 2.07
2003-02-19 X-dag halvårsutdelning AZN 3.99
2002-08-21 X-dag halvårsutdelning AZN 2.21
2002-02-20 X-dag halvårsutdelning AZN 5.01
2001-08-22 X-dag halvårsutdelning AZN 2.44
2001-02-21 X-dag halvårsutdelning AZN 4.49
2000-09-04 X-dag halvårsutdelning AZN 2.1
2000-03-08 X-dag halvårsutdelning AZN 4.01
1999-09-06 X-dag halvårsutdelning AZN 1.89
1999-04-01 Split AZN 1:0.5045
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AstraZeneca är ett globalt läkemedelsbolag med fokus på forskning, utveckling och marknadsföring av receptbelagda läkemedel, primärt för behandling av sjukdomar inom terapiområdena som berör andningsvägar, hjärta/kärl/metabolism och cancer. Utöver huvudverksamheten är bolaget även aktiva inom autoimmunitet, neurovetenskap och infektion. AstraZeneca är verksamt inom samtliga globala regioner och har sitt huvudkontor i Cambridge, Storbritannien.
2024-04-17 09:01:18

Real-world effectiveness data on Beyfortus reinforce the impact of passive immunisation protecting infants from RSV hospitalisation.
Updated real-world data demonstrate continued risk of severe COVID-19 outcomes among immunocompromised populations.

AstraZeneca will showcase new clinical, real-world and early science data across its Vaccines & Immune Therapies portfolio at the 34[th] European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Barcelona, Spain from 27-30 April 2024. The company has 19 abstracts at the event, including four oral presentations and four late-breaking presentations, which will highlight the continued need to protect at-risk individuals from the increased burden of common infectious diseases and the important role of long-acting antibodies and vaccines.

Data will be presented featuring:
  • Real-world data on effectiveness of Beyfortus (nirsevimab), a long-acting antibody, in the prevention of hospitalisation due to respiratory syncytial virus (RSV)
  • Updated real-world evidence demonstrating the continued disproportionate burden of COVID-19 infection on immunocompromised individuals, highlighting the need for additional protection
  • Pharmacokinetic and safety data on sipavibart, an investigational long-acting antibody for the prevention of COVID-19 in immunocompromised individuals
  • Research on early pipeline assets, including a late-breaking oral presentation on a novel mRNA-VLP vaccine platform and data on a monoclonal antibody to prevent recurrent C. difficile infection

Iskra Reic, Executive Vice President, Vaccines and Immune Therapies, AstraZeneca, said: "We are excited to share data at ECCMID showcasing the progress across our early- and late-stage Vaccines and Immune Therapies portfolio and our ambition to deliver long-lasting immunity to protect against infectious diseases with differentiated antibodies and vaccines. As well as our innovative science, we are proud of the difference our preventative therapeutics are making in reducing the burden of respiratory infections, with new real-world data highlighting the effectiveness of our long-acting antibody Beyfortus in preventing infant hospitalisations due to RSV. In addition, our data provide evidence that immunocompromised individuals continue to face a significant and disproportionate burden from COVID-19, highlighting the need for additional protection."

Real-world evidence highlighting the impact of Beyfortus in preventing RSV-related hospitalisations
New real-world data from NIRSE-GAL, an investigator-initiated, population-based three-year follow up study in the Galicia community in Spain, looked at the effectiveness of the 2023/2024 Beyfortus immunisation campaign in a broad infant population in reducing RSV-related hospitalisations.[1] The data add to the existing body of evidence that reinforces the high efficacy of Beyfortus from clinical trials resulting in protection against hospitalisation for RSV-associated lower respiratory tract infection (LRTI).

The significant burden of COVID-19 on the immunocompromised
Five presentations, including one oral, will highlight the ongoing risk and healthcare burden of COVID-19 on immunocompromised individuals. Data will include updated analyses from INFORM, a retrospective health database study in England, examining the continued increased risk of severe COVID-19 outcomes in several different immunocompromised populations despite receiving multiple COVID-19 vaccinations.[2-3] Real-world data from the COVIDRIVE study platform (run by the id.DRIVE public-private partnership) highlight the disproportionately high prevalence of immunocompromising conditions in SARS-CoV-2-positive hospitalised patients with severe acute respiratory infection in Europe.[4-6]

Key AstraZeneca presentations during ECCMID

Abstract title Presentation details
Universal Late-breaking oral sessionDate:
prophylaxis with 29/04/2024Time: 11:00 - 12:00
nirsevimab for CET
prevention of
due to respiratory
syncytial virus. A
longitudinal study
in Galicia Spain
Pharmacokinetics Late-breaking posterDate:
and safety of the 30/04/2024Time: 12:00 - 13:30
antibody AZD3152
are consistent
with those of
Sentinel cohort Poster sessionDate:
safety of 27/04/2024Time: 12:00 - 13:30
AZD5156/AZD3152 CET
from the phase 1/3
for COVID-19
prevention in
participants with
immune impairment
COVID-19 Real
-world evidence  
Individuals with Oral sessionDate:
multiple sclerosis 27/04/2024Time: 08:30 - 10:30
are at high risk CET
for COVID-19
and death despite
high rates of
results from the
England INFORM
Continued Poster sessionDate:
increased risk of 27/04/2024Time: 12:00 - 13:30
and death in
despite receipt of
≥4 vaccine doses:
updated 2023
results from
health database
study in England
High prevalence of Poster sessionDate:
immunocompromising 27/04/2024Time: 12:00 - 13:30
conditions among CET
patients with
severe acute
including SARS-CoV
-2: results from a
multicentre, test
-negative case
-control study
Immunocompromise, Poster sessionDate:
cancer and other 27/04/2024Time: 12:00 - 13:30
comorbidities in CET
patients with
severe acute
infection testing
positive versus
negative for SARS
-CoV-2: a post hoc
analysis of
from May 2021 to
May 2023
COVIDRIVE: a Poster sessionDate:
European public 27/04/2024Time: 12:00 - 13:30
-private CET
partnership for
generating real
-world evidence on
the effectiveness
of COVID-19
Early Science
An mRNA vaccine Late-breaking oral sessionDate:
expressing a self 27/04/2024Time: 14:45 - 15:45
-assembling virus CET
-like particle
antigen provides a
more potent,
durable and
broader immune
response to SARS
-CoV-2 in animal
models vs native
mRNA vaccines
Anti-toxin B Poster sessionDate:
neutralizing mAb 30/04/2024Time: 12:00 - 13:30
AZD5148 provides CET
protection in a
gnotobiotic piglet


Beyfortus (nirsevimab) is a single dose long-acting antibody, developed and commercialised in partnership by AstraZeneca and Sanofi using AstraZeneca's YTE extended-half-life technology. It is designed to protect infants born during or entering their first RSV season and for children up to 24 months of age who remain vulnerable to severe RSV disease through their second RSV season.  Beyfortus, provided directly to newborns and infants as a single dose, offers rapid protection via an antibody to help prevent LRTD caused by RSV, without requiring activation of the immune system.[7]

Beyfortus administration can be timed to the start of the RSV season.[7]

Beyfortus was granted regulatory designations to facilitate expedited development by several major regulatory agencies around the world. Beyfortus has been approved for use in the European Union, China and Japan and received approval by the US Food and Drug Administration following a unanimous recommendation by the Antimicrobial Drugs Advisory Committee. Beyfortus is recommended by the Advisory Committee on Immunization Practices for broad infant use and was included in the Vaccines for Children programme in the US.[7] Early data from the US Centers for Disease Control and Prevention, show that in the 2023/4 RSV season, Beyfortus was associated with a 90% reduction against RSV-associated hospitalisation among infants in their first RSV season.[8]

Sipavibart (formerly AZD3152) is an investigational long-acting monoclonal antibody (LAAB) against COVID-19. Sipavibart was designed to provide broad and potent coverage across Omicron and ancestral viral variants by neutralising spike protein interaction with the host receptor ACE2.[9]

Sipavibart was derived from B-cells donated by convalescent patients after SARS-CoV-2 infection. Sipavibart has been engineered using the same antibody scaffold as Evusheld and was optimised with the same half-life extension and reduced Fc effector function and complement C1q binding platform. The reduced Fc effector function aims to minimise the risk of antibody-dependent enhancement of disease - a phenomenon in which virus-specific antibodies promote, rather than inhibit, infection and/or disease.[10]

Sipavibart was acquired by AstraZeneca in May 2022 from RQ Biotechnology (https://www.astrazeneca.com/media-centre/press-releases/2022/astrazeneca-signs-licence-agreement-with-rq-biotechnology-for-monoclonal-antibodies-against-covid-19.html).

The safety and efficacy of sipavibart is being studied in the global SUPERNOVA COVID-19 prevention trial, with data anticipated in the first half of 2024.

AstraZeneca (LSE/STO/Nasdaq: AZN) is a global, science-led biopharmaceutical company that focuses on the discovery, development, and commercialisation of prescription medicines in Oncology, Rare Diseases, and BioPharmaceuticals, including Cardiovascular, Renal & Metabolism, and Respiratory & Immunology. Based in Cambridge, UK, AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. Please visit astrazeneca.com (http://www.astrazeneca.com/) and follow the Company on social media @AstraZeneca (https://www.linkedin.com/company/astrazeneca).

For details on how to contact the Investor Relations Team, please click here (https://www.astrazeneca.com/investor-relations.html#Contacts). For Media contacts, click here (https://www.astrazeneca.com/media-centre/contacts.html).


1. Mallah N, et al. Universal prophylaxis with nirsevimab for prevention of infant hospitalizations due to respiratory syncytial virus. A longitudinal study in Galicia Spain. Oral Presentation. 34[th] ECCMID Global; 29 April 2024; Barcelona, Spain.
2. Dube S, et al. Individuals with multiple sclerosis are at high risk for COVID-19 hospitalization and death despite high rates of vaccination: results from the England INFORM study. Oral Presentation. 34th ECCMID Global; 27 April 2024; Barcelona, Spain.
3. Dube S, et al. Continued increased risk of COVID-19 hospitalisation and death in immunocompromised individuals despite receipt of ≥4 vaccine doses: updated 2023 results from INFORM, a retrospective health database observational study in England. Poster P0409. 34th ECCMID Global; 27 April 2024; Barcelona, Spain.
4. Bollaerts K, et al. COVIDRIVE: a European public-private partnership for generating real-world evidence on the effectiveness of COVID-19 vaccines. Poster P0380. 34th ECCMID Global; 27 April 2024; Barcelona, Spain.
5. Meeraus W, et al. High prevalence of immunocompromising conditions among patients with severe acute respiratory infection, including SARS-CoV-2: results from a multicentre, test-negative case-control study. Poster P0381. 34th ECCMID Global; 27 April 2024; Barcelona, Spain.
6. Meeraus W, et al. Immunocompromise, cancer and other comorbidities in patients with severe acute respiratory infection testing positive versus negative for SARS-CoV-2: a post hoc analysis of COVIDRIVE data from May 2021 to May 2023. Poster P0382. 34th ECCMID Global; 27 April 2024; Barcelona, Spain.
7. Jones JM, et al. Use of nirsevimab for the prevention of respiratory syncytial virus disease among infants and young children: recommendations of the Advisory Committee on Immunization Practices - United States, 2023. MMWR Morb Mortal Wkly Rep. 2023;72(34):920-925.
8. Moline HL, et al. Early Estimate of Nirsevimab Effectiveness for Prevention of Respiratory Syncytial Virus-Associated Hospitalization Among Infants Entering Their First Respiratory Syncytial Virus Season - New Vaccine Surveillance Network, October 2023-February 2024. MMWR Morb Mortal Wkly Rep. 2024;73:209-214.
9. Francica JR, et al. 1355. The SARS-CoV-2 Monoclonal Antibody AZD3152 Potently Neutralizes Historical and Emerging Variants and is Being Developed for the Prevention and Treatment of COVID-19 in High-risk Individuals. Open Forum Infect Dis. 2023 Nov 27;10(Suppl 2):ofad500.1192. doi: 10.1093/ofid/ofad500.1192.
10. Van Erp EA, et al. Fc-Mediated Antibody Effector Functions During Respiratory Syncytial Virus    Infection and Disease. Front Immunol. 2019;10(March).