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Kursutveckling och likviditet under dagen för detta pressmeddelande

Kalender

2024-08-20 Kvartalsrapport 2024-Q2
2024-04-11 Årsstämma 2024
2024-04-04 Bokslutskommuniké 2023
2023-12-06 Split ORPHA 1000:1
2023-11-02 Extra Bolagsstämma 2023
2023-09-12 Kvartalsrapport 2023-Q2
2023-05-22 Ordinarie utdelning ORPHA 0.00 DKK
2023-05-17 Årsstämma 2023
2023-04-25 Bokslutskommuniké 2022
2022-09-26 Kvartalsrapport 2022-Q2
2022-06-29 Årsstämma 2022
2022-06-28 Ordinarie utdelning ORPHA 0.00 DKK
2022-06-07 Bokslutskommuniké 2021
2022-02-15 Extra Bolagsstämma 2022
2021-08-31 Kvartalsrapport 2021-Q2
2021-03-26 Ordinarie utdelning ORPHA 0.00 DKK
2021-03-25 Årsstämma 2021
2021-03-02 Bokslutskommuniké 2020
2020-09-21 Extra Bolagsstämma 2020
2020-08-28 Kvartalsrapport 2020-Q2
2020-03-27 Ordinarie utdelning ORPHA 0.00 DKK
2020-03-26 Årsstämma 2020
2020-02-28 Bokslutskommuniké 2019
2020-01-25 Extra Bolagsstämma 2019
2019-08-28 Kvartalsrapport 2019-Q2
2019-03-28 Ordinarie utdelning ORPHA 0.00 DKK
2019-03-27 Årsstämma 2019
2019-03-01 Bokslutskommuniké 2018
2018-08-28 Kvartalsrapport 2018-Q2
2018-04-13 Ordinarie utdelning ORPHA 0.00 DKK
2018-04-12 Årsstämma 2018
2018-03-15 Bokslutskommuniké 2017

Beskrivning

LandDanmark
ListaSmall Cap Copenhagen
SektorHälsovård
IndustriBioteknik
Orphazyme är verksamt inom biokemi. Bolaget är specialiserat mot forskning och utveckling av ovanliga sjukdomar där det finns en brist i funktionen hos värmekokproteiner. Tekniken baseras på arimoklomol, som stimulerar produktionen av värmekokproteiner i celler som upplever en ökad grad av stress och toxicitet. Sjukdomar som ämnar behandlas med bolagets produkter innefattar Gauchers sjukdom och amyotrofisk lateral skleros (ALS). Bolaget har sitt huvudkontor i Köpenhamn.
2020-11-03 22:44:06

Orphazyme A/S
Company announcement                                                                                       

No. 69/2020                                                                                                          
Company Registration No. 32266355


Copenhagen, Denmark, November 3, 2020 – With reference to company announcement no. 56/2020 dated September 29, 2020 regarding beginning of the stabilization period following the global offering (the “Global Offering”), consisting of an initial public offering of American Depositary Shares (the “ADSs”), each such ADS representing one ordinary share of Orphazyme, in the United States (the "U.S. Offering"), and a concurrent private placement of ordinary shares in Europe traded on Nasdaq Copenhagen A/S under the symbol “ORPHA” (the “European Private Placement”), Orphazyme A/S ("Orphazyme") has received notification that BofA Securities, Inc., who is acting as stabilizing manager in the Global Offering, that the stabilization period has ended and that (i) stabilization measures have been taken between September 29, 2020 and October 28, 2020 as set out in the attached end of stabilization notification from BofA Securities, Inc., given on its and its affiliate, BofA Securities Europe SA, behalf to Orphazyme, with respect to the ADSs admitted to trading on the Nasdaq Global Select Market in the United States under the symbol “ORPH”; (ii) no stabilization transactions have been taken in the ordinary shares of Orphazyme admitted to trading on Nasdaq Copenhagen A/S during the stabilization period; and (iii) the stabilization measures with respect to the ADSs set out in the attached mid-stabilization notification have been taken.

This company announcement does not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

BofA Securities, Inc., Cowen and Company, LLC and Guggenheim Securities, LLC acted as joint book-running managers for the offering referred to herein.


For additional information, please contact

Orphazyme A/S

Anders Vadsholt, CFO                                  +45 28 98 90 55


About Orphazyme A/S 
Orphazyme is a late-stage biopharmaceutical company pioneering the Heat-Shock Protein response for the treatment of neurodegenerative orphan diseases. The company is harnessing amplification of Heat-Shock Proteins (or HSPs) in order to develop and commercialize novel therapeutics for diseases caused by protein misfolding, protein aggregation, and lysosomal dysfunction, including lysosomal storage diseases and neuromuscular degenerative diseases. Arimoclomol, the company’s lead candidate, is in clinical development for four orphan diseases: Niemann-Pick disease Type C (NPC), Amyotrophic Lateral Sclerosis (ALS), sporadic Inclusion Body Myositis (sIBM) and Gaucher disease. Orphazyme is headquartered in Denmark and has operations in the U.S. and Switzerland. Orphazyme’s shares are listed on Nasdaq U.S. (ORPH) and Nasdaq Copenhagen (ORPHA). 

About arimoclomol 
Arimoclomol is an investigational drug candidate that amplifies the production of Heat-Shock Proteins (HSPs). HSPs can rescue defective misfolded proteins, clear protein aggregates, and improve the function of lysosomes. Arimoclomol is administered orally, crosses the blood-brain barrier, and has now been studied in seven phase 1, four phase 2 and one pivotal phase 2/3 trial. Arimoclomol is in clinical development for NPC, Gaucher Disease, sIBM, and ALS. Arimoclomol has received orphan drug designation (ODD) for NPC, sIBM, and ALS in the US and EU. Arimoclomol has received fast-track designation (FTD) from the U.S. Food and Drug Administration (FDA) for NPC, sIBM and ALS. In addition, arimoclomol has received breakthrough therapy designation (BTD) and rare-pediatric disease designation (RPDD) from the FDA for NPC.

Forward-looking statement 
This company announcement may contain certain forward-looking statements, including relating to the terms of the proposed offering, the Extraordinary General Meeting and the completion of the proposed offering. Although the Company believes its expectations are based on reasonable assumptions, all statements other than statements of historical fact included in this company announcement about future events are subject to (i) change without notice and (ii) factors beyond the Company’s control. These statements may include, without limitation, any statements preceded by, followed by, or including words such as “target,” “believe,” “expect,” “aim,” “intend,” “may,” “anticipate,” “estimate,” “plan,” “project,” “will,” “can have,” “likely,” “should,” “would,” “could”, and other words and terms of similar meaning or the negative thereof. Forward-looking statements are subject to inherent risks and uncertainties beyond the Company’s control that could cause the Company’s actual results, performance, or achievements to be materially different from the expected results, performance, or achievements expressed or implied by such forward-looking statements. Except as required by law, the Company assumes no obligation to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from those anticipated in the forward-looking statements, even if new information becomes available in the future.  


Mid-stabilization Period Announcement 

Further to the pre-stabilization period announcement dated September 28, 2020 (ET) / September 29, 2020 (CET), BofA Securities, Inc. (Joshua Plump, telephone +1 646-855-6765) and BofA Securities Europe SA, (Andrew Briscoe, +44 (0) 7418 937979) hereby give notice that the Stabilization Agents named below undertook stabilization (within the meaning of Article 3.2(d) of the Market Abuse Regulation (EU/596/2014)) in relation to the offer of the following securities, as set out below.

The securities:
Issuer:Orphazyme A/S
Securities:American Depositary Shares (“ADS”) each representing one ordinary share (“Ordinary Share”) of nominal DKK 1 issued in the Issuer; and

Ordinary Shares in the Issuer
Offering size:3,966,146 ADS and 3,650,000 Ordinary shares (collectively, the “Global Offering”)
Offer price:USD 11.00 per ADS and DKK 70.1844 per Ordinary Share
Listing Markets:The Nasdaq Global Select Market (NSDQ) in the United States (with respect to the ADSs); and

The Nasdaq Copenhagen A/S in Denmark (with respect to the Ordinary Shares)
Ticker:ORPH (Nasdaq Global Select Market)

ORPHA (Nasdaq Copenhagen A/S)
Stabilization:
Stabilization Agents:BofA Securities, Inc. with respect to ADSs on Nasdaq Global Select Market in the United States

One Bryant Park

New York, New York 10036

United States

 

BofA Securities Europe SA with respect to Ordinary Shares on Nasdaq Copenhagen A/S in Denmark

51 rue La Boétie,

75008 Paris

France


ADS Stabilization Transactions
Date and time (ET)QuantityPriceCurrencyStabilization Transaction Venue
10/27/2020 09:30:0154910.59USDNSDQ
10/27/2020 10:00:3910010.59USDSGMT
10/27/2020 10:01:4110010.59USDSGMT
10/27/2020 10:02:0310010.59USDSGMT
10/27/2020 10:02:4520010.59USDLATS
10/27/2020 10:03:1910010.59USDSGMT
10/27/2020 10:03:5410010.59USDSGMT
10/27/2020 10:04:2910010.59USDSGMT
10/27/2020 10:05:2010010.59USDSGMT
10/27/2020 10:06:2710010.59USDEBXL
10/27/2020 10:06:2710010.59USDLATS
10/27/2020 10:06:4910010.59USDSGMT
10/27/2020 10:07:2510010.59USDSGMT
10/27/2020 10:07:5910010.59USDSGMT
10/27/2020 10:08:1510010.58USDSGMT
10/27/2020 10:08:3210010.58USDSGMT
10/27/2020 10:09:4520010.59USDUBSA
10/27/2020 10:10:2420010.59USDLATS
10/27/2020 10:11:2310010.59USDSGMT
10/27/2020 10:13:5410010.59USDSGMT
10/27/2020 10:14:3720010.59USDLATS
10/27/2020 10:15:1410010.51USDJPMX
10/27/2020 10:17:2210010.59USDSGMT
10/27/2020 10:17:5130010.59USDLATS
10/27/2020 10:18:4310010.59USDSGMT
10/27/2020 10:19:0210010.58USDSGMT
10/27/2020 10:19:2010010.58USDSGMT
10/27/2020 10:19:2920010.59USDLATS
10/27/2020 10:19:4410010.51USDKCGM
10/27/2020 10:22:3910010.58USDEBXL
10/27/2020 10:22:3910010.58USDLATS
10/27/2020 10:23:1230010.59USDEBXL
10/27/2020 10:23:5910010.59USDSGMT
10/27/2020 10:24:3010010.59USDSGMT
10/27/2020 10:24:4910010.59USDUBSA
10/27/2020 10:24:4910010.59USDLATS
10/27/2020 10:25:2310010.59USDSGMT
10/27/2020 10:26:1610010.59USDEBXL
10/27/2020 10:26:1610010.59USDLATS
10/27/2020 10:28:5010010.59USDEBXL
10/27/2020 10:28:5010010.59USDUBSA
10/27/2020 10:30:2210010.55USDEDGX
10/27/2020 10:32:5620010.57USDNSDQ
10/27/2020 10:33:1910010.55USDNSDQ
10/27/2020 10:38:1610010.55USDEBXL
10/27/2020 10:38:1610010.55USDLATS
10/27/2020 10:40:0010010.55USDUBSA
10/27/2020 10:41:0110010.53USDNSDQ
10/27/2020 10:46:4110010.54USDBATS
10/27/2020 10:46:4210010.54USDUBSA
10/27/2020 10:47:0710010.50USDNSDQ
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10/27/2020 10:47:4310010.50USDNSDQ
10/27/2020 10:48:0110010.49USDNSDQ
10/27/2020 10:48:0310010.49USDNSDQ
10/27/2020 10:50:5110010.43USDIEXG
10/27/2020 11:09:1310010.49USDSGMT
10/27/2020 11:09:2310010.49USDSGMT
10/27/2020 11:18:0510010.49USDBATS
10/27/2020 11:18:0510010.49USDBATS
10/27/2020 11:18:0510010.49USDNQBX
10/27/2020 11:20:5710010.43USDARCX
10/27/2020 11:21:0010010.43USDARCX
10/27/2020 11:21:0210010.43USDARCX
10/27/2020 11:21:0410010.43USDARCX
10/27/2020 11:21:0410010.43USDARCX
10/27/2020 11:21:0410010.43USDARCX
10/27/2020 11:21:0510010.43USDARCX
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10/27/2020 11:21:2010010.43USDARCX
10/27/2020 11:46:0310010.40USDEBXL
10/27/2020 11:46:0310010.38USDUBSA
10/27/2020 11:49:2810010.40USDEBXL
10/27/2020 11:49:2810010.38USDUBSA
10/27/2020 11:51:2610010.40USDSGMT
10/27/2020 11:52:5110010.39USDEBXL
10/27/2020 11:54:5520010.40USDNSDQ
10/27/2020 11:55:2810010.28USDNSDQ
10/27/2020 12:01:2110010.28USDNSDQ
10/27/2020 12:02:466010.31USDNSDQ
10/27/2020 12:02:4620010.32USDBATS
10/27/2020 12:02:464010.32USDNSDQ
10/27/2020 12:06:0410010.42USDNITE
10/27/2020 12:09:262010.32USDNSDQ
10/27/2020 12:09:266010.32USDNSDQ
10/27/2020 12:09:2612010.42USDARCX
10/27/2020 12:11:3310010.40USDEBXL
10/27/2020 12:12:4310010.39USDNSDQ
10/27/2020 12:12:5110010.39USDNSDQ
10/27/2020 12:12:521010.40USDNSDQ
10/27/2020 12:12:5210010.40USDNSDQ
10/27/2020 12:12:528010.40USDNSDQ
10/27/2020 12:12:5310010.41USDBATS
10/27/2020 12:12:5310010.41USDNSDQ
10/27/2020 12:13:004010.41USDARCX
10/27/2020 12:13:006010.42USDARCX
10/27/2020 12:13:1310010.40USDNSDQ
10/27/2020 12:13:582010.40USDNSDQ
10/27/2020 12:13:586010.41USDNSDQ
10/27/2020 12:13:5812010.42USDARCX
10/27/2020 12:19:3610010.41USDARCX
10/27/2020 12:19:3630010.42USDARCX
10/27/2020 12:19:372010.41USDNSDQ
10/27/2020 12:19:371010.41USDNSDQ
10/27/2020 12:19:3717010.42USDARCX
10/27/2020 12:19:4410010.46USDBATS
10/27/2020 12:19:4510010.48USDNSDQ
10/27/2020 12:19:5110010.49USDNITE
10/27/2020 12:21:4020010.48USDNSDQ
10/27/2020 12:23:0010010.49USDNITE
10/27/2020 12:26:0010010.49USDUBSA
10/27/2020 12:26:0010010.49USDLATS
10/27/2020 12:30:2910010.49USDEBXL
10/27/2020 12:30:2910010.49USDLATS
10/27/2020 12:31:4810010.48USDNSDQ
10/27/2020 12:32:542010.40USDNSDQ
10/27/2020 12:32:548010.40USDNSDQ
10/27/2020 12:33:3610010.47USDNSDQ
10/27/2020 12:35:3010010.48USDNSDQ
10/27/2020 12:35:3010010.48USDNSDQ
10/27/2020 12:36:1210010.48USDNSDQ
10/27/2020 12:36:4910010.49USDMLIX
10/27/2020 12:37:4110010.50USDUBSA
10/27/2020 12:37:4110010.50USDLATS
10/27/2020 12:38:4910010.49USDMLIX
10/27/2020 12:39:3210010.50USDLATS
10/27/2020 12:39:3210010.50USDEBXL
10/27/2020 12:40:5810010.50USDUBSA
10/27/2020 12:40:5810010.50USDLATS
10/27/2020 12:43:5310010.50USDJSJX
10/27/2020 12:46:2310010.50USDJSJX
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10/27/2020 12:49:0520010.50USDUBSA
10/27/2020 12:49:0510010.50USDLATS
10/27/2020 12:52:0810010.50USDJSJX
10/27/2020 12:54:0310010.50USDJSJX
10/27/2020 12:56:0210010.50USDJSJX
10/27/2020 12:57:2610010.50USDLATS
10/27/2020 12:57:2610010.50USDEBXL
10/27/2020 12:58:3510010.50USDJSJX
10/27/2020 13:00:4630010.50USDNITE
10/27/2020 13:01:3710010.50USDJSJX
10/27/2020 13:02:5710010.50USDLATS
10/27/2020 13:02:5710010.50USDEBXL
10/27/2020 13:03:4210010.50USDJSJX
10/27/2020 13:05:5910010.50USDJSJX
10/27/2020 13:06:4410010.43USDNSDQ
10/27/2020 13:07:0010010.49USDNITE
10/27/2020 13:08:0010010.48USDNSDQ
10/27/2020 13:08:331010.49USDNSDQ
10/27/2020 13:08:332010.49USDNSDQ
10/27/2020 13:08:337010.49USDNSDQ
10/27/2020 13:09:577010.49USDBATS
10/27/2020 13:09:5710010.48USDNSDQ
10/27/2020 13:09:571010.49USDNSDQ
10/27/2020 13:09:572010.49USDNSDQ
10/27/2020 13:10:0010010.49USDNSDQ
10/27/2020 13:11:2910010.50USDLATS
10/27/2020 13:11:2910010.50USDEBXL
10/27/2020 13:11:3010010.50USDUBSA
10/27/2020 13:11:3010010.50USDEBXL
10/27/2020 13:12:0110010.50USDLATS
10/27/2020 13:13:0010010.50USDUBSA
10/27/2020 13:13:0010010.50USDLATS
10/27/2020 13:15:0020010.50USDEBXL
10/27/2020 13:16:0020010.50USDUBSA
10/27/2020 13:16:0010010.50USDLATS
10/27/2020 13:18:0010010.50USDUBSA
10/27/2020 13:18:0010010.50USDEBXL
10/27/2020 13:19:0820010.50USDLATS
10/27/2020 13:20:0010010.50USDUBSA
10/27/2020 13:20:0010010.50USDEBXL
10/27/2020 13:21:0010010.50USDUBSA
10/27/2020 13:22:0010010.50USDMLIX
10/27/2020 13:22:0010010.50USDLATS
10/27/2020 13:24:0010010.50USDUBSA
10/27/2020 13:24:0010010.50USDLATS
10/27/2020 13:25:0020010.50USDUBSA
10/27/2020 13:25:0010010.47USDNSDQ
10/27/2020 13:28:0010010.50USDEBXL
10/27/2020 13:28:0020010.50USDUBSA
10/27/2020 13:28:3710010.50USDUBSA
10/27/2020 13:30:0010010.50USDUBSA
10/27/2020 13:30:0020010.50USDLATS
10/27/2020 13:31:0010010.50USDUBSA
10/27/2020 13:32:0010010.50USDMLIX
10/27/2020 13:32:0010010.50USDLATS
10/27/2020 13:32:0110010.47USDNSDQ
10/27/2020 13:33:0010010.50USDUBSA
10/27/2020 13:33:4410010.50USDUBSA
10/27/2020 13:34:0110010.50USDUBSA
10/27/2020 13:34:2620010.50USDLATS
10/27/2020 13:35:0720010.50USDARCX
10/27/2020 13:35:2910010.56USDBATS
10/27/2020 13:35:2910010.56USDBATS
10/27/2020 13:35:2910010.56USDNSDQ
10/27/2020 13:35:2910010.56USDNSDQ
10/27/2020 13:35:2910010.51USDEBXL
10/27/2020 13:35:3710010.57USDNITE
10/27/2020 13:36:5910010.56USDCODA
10/27/2020 13:37:0710010.56USDEBXL
10/27/2020 13:38:0110010.56USDSGMT
10/27/2020 13:38:5410010.56USDSGMT
10/27/2020 13:39:3110010.56USDSGMT
10/27/2020 13:40:4610010.56USDSGMT
10/27/2020 13:42:2910010.56USDSGMT
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10/27/2020 13:45:0010010.56USDSGMT
10/27/2020 13:45:0010010.56USDSGMT
10/27/2020 13:45:0110010.55USDNSDQ
10/27/2020 13:46:1310010.56USDEDGX
10/27/2020 13:47:3910010.57USDNSDQ
10/27/2020 13:48:2310010.57USDBATS
10/27/2020 13:49:0010010.60USDUBSA
10/27/2020 13:50:0010010.60USDARCX
10/27/2020 13:50:4310010.60USDUBSA
10/27/2020 13:52:0010010.60USDEBXL
10/27/2020 13:52:0010010.60USDUBSA
10/27/2020 13:53:0020010.60USDUBSA
10/27/2020 13:53:2110010.60USDUBSA
10/27/2020 13:56:0020010.60USDEBXL
10/27/2020 13:56:0010010.60USDUBSA
10/27/2020 13:58:2610010.59USDUBSA
10/27/2020 13:59:0110010.59USDUBSA
10/27/2020 13:59:5010010.59USDUBSA
10/27/2020 14:00:1710010.60USDLATS
10/27/2020 14:00:1710010.60USDLATS
10/27/2020 14:01:5510010.55USDNSDQ
10/27/2020 14:01:5510010.55USDNSDQ
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10/27/2020 14:01:5510010.55USDNSDQ
10/27/2020 14:01:5510010.52USDNSDQ
10/27/2020 14:01:5510010.52USDNSDQ
10/27/2020 14:02:5610010.50USDEDGX
10/27/2020 14:03:0110010.59USDMLIX
10/27/2020 14:04:0110010.50USDEDGX
10/27/2020 14:05:3910010.59USDMLIX
10/27/2020 14:07:0120010.60USDNITE
10/27/2020 14:09:0010010.59USDMLIX
10/27/2020 14:10:0110010.59USDMLIX
10/27/2020 14:12:089710.53USDBATS
10/27/2020 14:12:0810010.52USDNSDQ
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10/27/2020 14:15:0010010.59USDLATS
10/27/2020 14:16:5210010.56USDMLIX
10/27/2020 14:18:4910010.59USDUBSA
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10/27/2020 14:22:5110010.60USDEBXL
10/27/2020 14:22:5110010.59USDUBSA
10/27/2020 14:22:5110010.60USDUBSA
10/27/2020 14:26:3520010.60USDEBXL
10/27/2020 14:28:0110010.56USDMLIX
10/27/2020 14:29:4310010.54USDCODA
10/27/2020 14:30:411010.51USDNSDQ
10/27/2020 14:30:4210010.54USDSGMT
10/27/2020 14:32:2610010.54USDLATS
10/27/2020 14:34:0110010.54USDKCGM
10/27/2020 14:35:0110010.54USDUBSA
10/27/2020 14:36:0010010.54USDUBSA
10/27/2020 14:39:4310010.56USDSGMT
10/27/2020 14:41:2810010.57USDLATS
10/27/2020 14:41:2810010.56USDNSDQ
10/27/2020 14:41:5510010.56USDMLIX
10/27/2020 14:44:0410010.56USDMLIX
10/27/2020 14:44:0410010.55USDNSDQ
10/27/2020 14:44:042010.56USDNSDQ
10/27/2020 14:44:048010.56USDBATS
10/27/2020 14:46:152010.56USDBATS
10/27/2020 14:46:1510010.57USDBATS
10/27/2020 14:46:1510010.56USDNSDQ
10/27/2020 14:46:1510010.57USDNSDQ
10/27/2020 14:47:4620010.60USDNITE
10/27/2020 14:47:5420010.51USDNSDQ
10/27/2020 14:47:5410010.51USDNSDQ
10/27/2020 14:47:541010.51USDNSDQ
10/27/2020 14:47:5410010.51USDNSDQ
10/27/2020 14:47:5410010.51USDNSDQ
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10/28/2020 15:21:041009.87USDIEXG
10/28/2020 15:22:352009.87USDIEXG
10/28/2020 15:24:161009.87USDIEXG
10/28/2020 15:25:001009.87USDIEXG
10/28/2020 15:25:401009.87USDIEXG
10/28/2020 15:26:201009.87USDIEXG
10/28/2020 15:26:502009.87USDIEXG
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10/28/2020 15:28:302009.87USDIEXG
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10/28/2020 15:29:102009.87USDIEXG
10/28/2020 15:29:421009.87USDIEXG
10/28/2020 15:30:382009.87USDIEXG
10/28/2020 15:31:192009.87USDIEXG
10/28/2020 15:32:461009.87USDIEXG
10/28/2020 15:33:231009.87USDIEXG
10/28/2020 15:34:021009.87USDIEXG
10/28/2020 15:34:341009.88USDIEXG
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10/28/2020 15:36:071009.87USDIEXG
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10/28/2020 15:37:371009.87USDIEXG
10/28/2020 15:38:561009.87USDIEXG
10/28/2020 15:39:221009.83USDNSDQ
10/28/2020 15:39:221009.83USDNSDQ
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10/28/2020 15:39:221009.83USDNSDQ
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10/28/2020 15:39:221009.83USDNSDQ
10/28/2020 15:44:321009.80USDSGMT
10/28/2020 15:44:321009.75USDJPMX
10/28/2020 15:45:051009.74USDIEXG
10/28/2020 15:45:191009.74USDNSDQ
10/28/2020 15:45:331009.74USDNSDQ
10/28/2020 15:45:501009.74USDNSDQ
10/28/2020 15:46:081009.74USDNSDQ
10/28/2020 15:46:431009.71USDIEXG
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10/28/2020 15:47:281009.74USDNSDQ
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10/28/2020 15:48:072009.75USDNSDQ
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10/28/2020 15:49:392009.75USDNSDQ
10/28/2020 15:50:00159.72USDEDGX
10/28/2020 15:50:0059.72USDEDGX
10/28/2020 15:50:121009.75USDNSDQ
10/28/2020 15:50:211009.72USDEDGX
10/28/2020 15:50:21809.72USDEDGX
10/28/2020 15:50:21209.72USDEDGX
10/28/2020 15:50:32919.69USDNSDQ
10/28/2020 15:51:081009.67USDNSDQ
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10/28/2020 15:51:571009.69USDNSDQ
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10/28/2020 15:52:302009.68USDNSDQ
10/28/2020 15:52:371009.69USDIEXG
10/28/2020 15:52:371009.68USDARCX
10/28/2020 15:52:371009.68USDARCX
10/28/2020 15:54:031009.68USDIEXG
10/28/2020 15:54:031009.67USDNSDQ
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10/28/2020 15:56:071009.70USDIEXG
10/28/2020 15:56:072009.69USDNSDQ
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10/28/2020 15:56:18129.65USDNSDQ
10/28/2020 15:56:18889.65USDNSDQ
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10/28/2020 15:56:25109.63USDARCX
10/28/2020 15:56:34909.63USDARCX
10/28/2020 15:56:431009.63USDARCX
10/28/2020 15:57:011009.61USDBATS
10/28/2020 15:58:201009.68USDSGMT
10/28/2020 15:58:24719.67USDNSDQ
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10/28/2020 15:58:491009.71USDITGI
10/28/2020 15:58:511009.71USDNITE
10/28/2020 15:59:021009.71USDBYXX
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10/28/2020 15:59:092009.74USDNITE
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10/28/2020 15:59:142009.74USDNITE
10/28/2020 15:59:161009.74USDEBXL
10/28/2020 15:59:211009.74USDNITE
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10/28/2020 15:59:251009.74USDUBSA
10/28/2020 15:59:251009.74USDNITE
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10/28/2020 15:59:324009.74USDNITE
10/28/2020 15:59:353009.74USDNITE
10/28/2020 15:59:391009.755USDEBXL
10/28/2020 15:59:391009.755USDLATS
10/28/2020 15:59:391009.755USDLATS
10/28/2020 15:59:391009.76USDITGI
10/28/2020 15:59:434009.76USDNITE
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10/28/2020 15:59:471009.76USDITGI
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10/28/2020 15:59:511009.73USDNSDQ
10/28/2020 15:59:511009.7USDNSDQ
10/28/2020 15:59:551009.7USDNSDQ
10/28/2020 15:59:55759.73USDNSDQ


End of Stabilization Notice

Pursuant to Article 6(3) of Commission Regulation (EC) 2016/1052 supplementing Article 5 of Regulation (EU) No 596/2014 of the European Parliament and of the Council with regard to regulatory technical standards for the conditions applicable to buy-back programmes and stabilization, BofA Securities, Inc. (Joshua Plump, telephone +1 646-855-6765) and BofA Securities Europe SA, (Andrew Briscoe, +44 (0) 7418 937979) hereby give notice that stabilization was undertaken by the Stabilizing Agents named below in relation to the offer of the following securities.

Issuer:Orphazyme A/S
Securities:American Depositary Shares (“ADS”) each representing one ordinary share (“Ordinary Share”) of nominal DKK 1 issued in the Issuer; and

Ordinary Shares in the Issuer*
Offering size:3,966,146 ADSs and 3,650,000 Ordinary shares (collectively, the “Global Offering”)
Offer price:USD 11.00 per ADS and DKK 70.1844 per Ordinary Share
Listing Markets:The Nasdaq Global Select Market in the United States (with respect to the ADSs); and

The Nasdaq Copenhagen A/S in Denmark (with respect to the Ordinary Shares)*
Stabilization trading venuesAMEX

ARCX

BATS

BIDS

BYXX

CODA

EBXL

EDGA

EDGX

GSA

IEXG

INCA

ITGI

JPMX

JSJX

KCGM

LATS

MLCO

MLIX

NITE

NQBX

NQPX

NSDQ

NYSE

SGMT

UBSA

XCIS

XSTM
Tickers:ORPH (Nasdaq Global Select Market)

ORPHA (Nasdaq Copenhagen A/S)
Stabilization Agents:BofA Securities, Inc. with respect to ADSs on Nasdaq Global Select Market in the United States

One Bryant Park

New York, New York 10036

United States

 

BofA Securities Europe SA with respect to Ordinary Shares on Nasdaq Copenhagen A/S in Denmark

51 rue La Boétie,

75008 Paris

France
Stabilization Period:September 29, 2020 to October 28, 2020

*No stabilization activities occurred in the ordinary shares on the Nasdaq Copenhagen A/S market or on any other trading venues.

ADS Stabilization Transactions
Trade Date (ET)Lowest Price Paid (USD)Highest Price Paid (USD)
9/29/20209.6010.80
10/2/202010.6110.90
10/6/202010.3210.785
10/7/202010.6610.80
10/8/202010.60510.75
10/9/202010.6110.97
10/12/202010.9111.00
10/13/202010.8110.94
10/14/202010.8811.00
10/15/202010.7410.99
10/16/202010.7510.94
10/19/202010.6810.94
10/20/202010.47510.86
10/21/202010.3010.59
10/22/202010.08510.30
10/23/202010.0010.29
10/26/202010.5010.87
10/27/202010.27510.6
10/28/20209.6110.28

As a consequence of the stabilization measures taken, BofA Securities, Inc. and the other underwriters will not exercise the overallotment option described in the final prospectus dated September 28, 2020 and filed with the Securities and Exchange Commission on September 29, 2020.

Important notice

This announcement is for information purposes only and does not constitute or form part of, and should not be construed as, an invitation or offer to underwrite, subscribe for or otherwise acquire or dispose of any securities of the Company in any jurisdiction.

This announcement is made in accordance with the principles and procedures of the Market Abuse Regulation (Commission Regulation (EU) no. 596/2014 of 16 April 2014), including delegated regulations, as amended from time to time, and is not intended for dissemination to the public in jurisdictions where a prior registration or approval is required. No steps have been taken, or will be taken, for the public offering of Ordinary Shares or ADSs in any jurisdiction other than the United States. The issue or sale of Ordinary Shares and ADSs, and the subscription for or purchase of Ordinary Shares and ADSs, may be subject to special legal or statutory restrictions in applicable jurisdictions. Orphazyme is not liable if these restrictions are not complied with by any other person.

The offering of the ADSs was made in the United States, only by means of a prospectus, which is on file with the Securities and Exchange Commission. A copy of the prospectus for such offering may be obtained at no cost by visiting EDGAR at www.sec.gov. Copies of the prospectus relating to the offering may be obtained from BofA Securities, NC1-004-03-43, 200 North College Street, 3rd floor, Charlotte, NC 28255-0001, Attn: Prospectus Department, or by email at dg.prospectus_requests@bofa.com; Cowen, c/o Broadridge Financial Solutions, Attn: Prospectus Department, 1155 Long Island Avenue, Edgewood, NY 11717, by email at  PostSaleManualRequests@broadridge.com or by telephone at (833) 297-2926; or Guggenheim Securities, Attention: Equity Syndicate Department, 330 Madison Avenue, 8th Floor, New York, NY 10017, by telephone at (212) 518-9544, or by email at GSEquityProspectusDelivery@guggenheimpartners.com.